
extraction
Although there are a variety of methods available, supercritical CO2 extraction is our method of choice when extracting active compounds from botanical material for several reasons. The more common methods utilize a series of volatile and toxic solvents to free the active compounds from the organic substrate. This can be particularly problematic since the resulting extracts retain solvent residues which compromise the purity of the extracted compound. With supercritical CO2, mild operating temperature ensures product stability and quality leaving extracts and spent biomass completely free of solvent residues and contaminants resulting in true “pharmaceutical grade” compounds. Supercritical CO2 is also universally accepted as a "friendly", clean and fully recyclable solvent where product recovery is accomplished via a simple pressure reduction leaving no hazardous residues whatsoever.


Supercritical Fluid Extraction
SFE Systems extract chemical compounds using supercritical carbon dioxide instead of an organic solvent. The supercritical fluid state occurs when a fluid is above its critical temperature (Tc) and critical pressure (Pc), when it is between the typical gas and liquid state. Manipulating the temperature and pressure of the fluid can solubilize the material of interest and selectively extract it. The sample is placed in an extraction vessel and pressurized with CO2 to dissolve the sample. Transferred to a fraction collector, the contents are depressurized and the CO2 loses its solvating power causing the desired material to precipitate. The condensed CO2 can then also be recycled to minimize the already tiny carbon footprint left by this process.